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胸外科手术肺漏气与术中出血的诊治:基于Delphi法制定的意大利胸外科学会专家共识

肺持续性漏气和术中出血的诊治是胸外科手术中常见的挑战之一。 More >>

中国香港胸外科现状简介

中国香港的胸外科早在20世纪50年代还是一个新兴的亚专科,主要关注于非... More >>

中国台湾医疗系统与胸外科发展

中国台湾位于南海以北,距大陆东南沿海约180公里,总面积3.6万平方公里... More >>

Cough Section more

Clinical Practice Guidelines for Diagnosis and Management of Cough—Chinese Thoracic Society (CTS) Asthma Consortium

Kefang Lai, Huahao Shen, Xin Zhou, Zhongmin Qiu, Shaoxi Cai, Kewu Huang, Qiuping Wang, Changzheng... More >>

Cough frequency monitors: can they discriminate patient from environmental coughs?

Stefan T. Kulnik, Natalie M. Williams, Lalit Kalra, John Moxham, Surinder S. Birring More >>

Endorsement

Journal of Thoracic Disease is endorsed by: The International COPD Coalition

The International COPD Coalition

The China Asthma Alliance

The China Asthma Alliance

The Brazilian Society of Thoracic Surgery (SBCT)

The Brazilian Society of Thoracic Surgery (SBCT)

The Italian Society of Thoracic Surgery (SICT)

The Italian Society of Thoracic Surgery (SICT)

The Italian VATS Group

The Italian VATS Group

The Global Alliance against Chronic Respiratory Diseases (GARD)

The Global Alliance against Chronic Respiratory Diseases (GARD)

The Hong Kong Society of Endosonography

The Hong Kong Society of Endosonography

Original Article

Effectiveness of S100 calcium-binding protein A12 combined with modified early warning score in the clinical diagnosis of adult community-acquired pneumonia
Xiao-Lian Zhou, Lu-Ying Shu, Qiao Liu, Jian Deng, Dan Wang, Duo Li
A comparison of GOLD 2019 and 2023 recommendations to contemporaneous real-world inhaler treatment patterns for chronic obstructive pulmonary disease management in Singapore
Rayan Alsuwaigh, Anthony Yii, Chee Hong Loh, Xiaomeng Xu, Priti Bahety, Aldo A. Navarro Rojas, Dominique Milea, Augustine Tee
The role of the female gender on mid-term outcome after coronary artery bypass grafting: a retrospective study
Paolo Nardi, Calogera Pisano, Carlo Bassano, Fabio Bertoldo, Dario Buioni, Vincenzo Labriola, Alessandro Cristian Salvati, Mattia Scognamiglio, Claudia Altieri, Giovanni Ruvolo
Impact of adjuvant chemotherapy on patients with stage IB non-small cell lung cancer with visceral pleural invasion
Bo-Guen Kim, Juwhan Choi, Sun-Kyung Lee, Sue In Choi, Chan Kwon Park, Jae Kyeom Sim, Hyun Lee, Sang-Heon Kim, Jang Won Sohn, Ho Joo Yoon, Sung Yong Lee, Dong Won Park
Direct oral anticoagulants compared with warfarin in patients with left ventricular thrombus: a cohort study from China
Yang Zhou, Xiaoxuan Zhang, Yang Lin, Wenxing Peng
Can a stapling device with bioabsorbable polyglycolic acid felt reduce intraoperative air leak?
Takashi Makino, Takuma Matsumura, Masakazu Kono, Yoichi Anami
Anatomical distribution and clinical significance of translobar bronchi, arteries, and veins hidden in the interlobar fissure
Wenzheng Xu, Zhihua Li, Zhicheng He, Chuan Gao, Shusheng Zhu, Weibing Wu, Liang Chen
Exploring diverse programmed cell-death patterns to develop a novel gene signature for predicting the prognosis of lung adenocarcinoma patients
Zhanming Ma, Yue Wang, Yaxin Yu, Fangqiu Fu, Yang Zhang
Histopathologic fate of resected pulmonary pure ground glass nodule: a systematic review and meta-analysis
Wongi Woo, Du-Young Kang, Yoon Jin Cha, Vincent Kipkorir, Seung Hwan Song, Duk Hwan Moon, Jae Il Shin, Sungsoo Lee
Imaging features and deep learning for prediction of pulmonary epithelioid hemangioendothelioma in CT images
Junfeng Huang, Shuojia Xie, Junjie Huang, Ziwen Zheng, Zikai Lin, Jinsheng Lin, Kailun Tang, Mingqiang Meng, Yulin Zhao, Wanzhe Liao, Chunping Liu, Yingying Gu, Shiyue Li, Huai Chen, Ruchong Chen
Palliation of malignant esophageal stent esophagorespiratory fistula with rigid bronchoscope and Y silicone trachea stent: experience with seven patients
Qixia Wang, Yanghuan Chen, Yihua Xu, Hang Xu, Xiaoting Cai, Runchen Wang, Zhiming Ye, Zijian Wen, Shiyue Li, Yu Chen
Comparison of outcomes of surgical and other invasive treatment modalities for malignant pleural effusion in patients with pleural carcinomatosis
Joshua Schramm, Elina Eslauer, Sameer Hammoudeh, Sebastian Stange, Zsolt Sziklavari
Anti-titin antibodies in a cohort of myasthenia gravis patients
João Moura, Ana Paula Sousa, Raquel Samões, Paula Carneiro, Esmeralda Neves, Ana Martins Silva, Ernestina Santos
Phenotypes of esophageal pressure response to the change of positive end-expiratory pressure in patients with moderate acute respiratory distress syndrome
Wei Cheng, Jing Jiang, Yun Long, Siyi Yuan, Yujing Sun, Zhanqi Zhao, Huaiwu He
What are the risk factors for postoperative home oxygen therapy in patients with lung cancer?
Takahiro Yamanaka, Yuichi Sakairi, Yuki Sata, Takahide Toyoda, Terunaga Inage, Kazuhisa Tanaka, Hidemi Suzuki, Yukiko Matsui, Ichiro Yoshino
High flow nasal oxygen vs. conventional oxygen therapy over respiratory oxygenation index after esophagectomy: an observational study
Cristian Deana, Massimo Vecchiato, Francesco Bellocchio, Annarita Tullio, Antonio Martino, Antonio Ziccarelli, Vincenzo Patruno, Marika Pascolo, Flavio Bassi, Marta Pontoni, Paola Raimondi, Lorenzo Cereser, Luigi Vetrugno, Roberto Petri, Alessandro Uzzau
Artificial intelligence (AI)-assisted chest computer tomography (CT) insights: a study on intensive care unit (ICU) admittance trends in 78 coronavirus disease 2019 (COVID-19) patients
Rudolf Bumm, Paolo Zaffino, Andras Lasso, Raúl San José Estépar, Steven Pieper, Jakob Wasserthal, Maria Francesca Spadea, Tsogyal Latshang, Nadine Kawel-Boehm, Adrian Wäckerlin, Raphael Werner, Gabriela Hässig, Markus Furrer, Ron Kikinis
Optimal therapeutic strategy for non-small cell lung cancer with thoracic extrathoracic metastasis: a study based on SEER database
Zhehao He, Xuqi Sun, Jinming Xu, Luming Wang, Jun Cheng, Wang Lv, Jian Hu
Compare three diagnostic criteria of progressive pulmonary fibrosis
Tao Chen, Chunfang Zeng
Fascial structure of the anterior mediastinum: the surgical figure of the sternopericardial ligament and the role of affixing the thymus to the pericardium
Kozo Nakanishi, Hidenori Goto
Predicting postoperative lung function using ventilation SPECT/CT in patients with lung cancer
Yong Ho Jeong, Hyun Lee, Hyo Jun Jang, Dong Won Park, Yun Young Choi, Soo Jin Lee
Surgical-decision making in the setting of unsuspected N2 disease: a cost-effectiveness analysis
Brian Mitzman, Thomas K. Varghese Jr, Wallace L. Akerley, Richard E. Nelson
Risk factor and correlation between postoperative serum myoglobin and acute kidney injury after pulmonary endarterectomy
Mingyuan Xu, Yanan Zhen, Zhaohua Zhang, Xia Zheng, Xiaopeng Liu, Jingwen Liu, Liang Yang, Zhidong Ye, Jianyan Wen, Peng Liu
Characteristics and patient-reported outcomes of long-term lung cancer survivors
Ana Fonseca, Mariana Antunes, João Firmino-Machado, Ana Barroso, Margarida Dias
Prognostic implication of Vasoactive Inotropic Score in adult patients with cardiogenic shock on veno-arterial extracorporeal membrane oxygenation
Yao Hu, Liangshan Wang, Feng Yang, Xiaomeng Wang, Shuai Zhang, Xing Hao, Hong Wang, Xiaotong Hou
A novel neoadjuvant therapy for early-stage non-small cell lung cancer in a mouse model
Lanlin Zhang, Jiangyuan Du, Xianghua Wu
Dietary habits and nutrition status in esophageal cancer patients after esophageal reconstruction
Yan He, Ya-Ya Wu, Wan Wei, Yong-Bo Yang, Yao Lin, Liang Dai
Pirfenidone and nintedanib attenuate pulmonary fibrosis in mice by inhibiting the expression of JAK2
Yan Yang, Xinmeng Wang, Jie Zhang
The association between patient preoperative disposition and outcomes after diagnostic lung biopsy
Adam R. Dyas, Christina M. Stuart, Yizhou Fei, Jake L. Cotton, Kathryn L. Colborn, Michael J. Weyant, Simran K. Randhawa, Elizabeth A. David, John D. Mitchell, Christopher D. Scott, Robert A. Meguid
Negative impact of ratio of the microvascular area to tumor area on the response to EGFR-TKI in non-small cell lung cancer with an EGFR mutation
Moriyasu Anai, Koichi Saruwatari, Kosuke Imamura, Kosuke Fujino, Takayuki Jodai, Shinya Sakata, Shinji Iyama, Yusuke Tomita, Sho Saeki, Hidenori Ichiyasu, Koei Ikeda, Makoto Suzuki, Takuro Sakagami
Liposomal bupivacaine intercostal block placed under direct vision reduces morphine use in thoracic surgery
Anupama Singh, Miles McAllister, Luis E. De León, Suden Kücükak, Matthew M. Rochefort, Emanuele Mazzola, Luisa Maldonado, Phillip M. Hartigan, Michael T. Jaklitsch, Scott J. Swanson, Raphael Bueno, Ashley L. Deeb, Namrata Patil
Early postoperative constrictive pericarditis in China: a single-center retrospective observational study
Jianhui Peng, He Wang, Keng Zhong, Jie Lu, Chengliang Cai, Fan Yang, Shangyi Yu, Lin Han, Zhiyun Xu, Guanxin Zhang
Perioperative morbidity and 3-year survival in non-intubated thoracoscopic surgery: a propensity matched analysis
Brooks V. Udelsman, Anna Jang, Ashok Muniappan, Peter L. Zhan, Xiaodong Bao, Tongyan Chen, Henning A. Gaissert
Low-normal free triiodothyronine as a predictor of post-operative atrial fibrillation after surgical coronary revascularization
Cuncun Hua, Pengfei Liu, Min Zhang, Jiayin Niu, Lefeng Wang, Guangzhen Zhong
Learning curve for complex segmentectomy via uniportal video-assisted thoracoscopic surgery for the treatment of early-stage lung cancer
Seha Ahn, Youngkyu Moon
Factors influencing the length of stay (LOS) undergoing robot-assisted thoracoscopic lung surgery in the setting of enhanced recovery after surgery (ERAS) protocol for pediatric patients: a retrospective study
Jiabin Fan, Yi Gao, Jialian Zhao, Liang Liang, Yue Jin, Haiyan Jin
Analysis of the hemostatic effect of preset wrapping technique for type A aortic dissection with abnormal coagulation
Zhixiang Cai, Tao Yan, Ben Zhang, Weida Zhang, Chenjie Su, Hanwei Chen, Xianyue Wang
HOXA5-induced lncRNA DNM3OS promotes human embryo lung fibroblast fibrosis via recruiting EZH2 to epigenetically suppress TSC2 expression
Hong Lv, Xingjia Qian, Zhengzheng Tao, Jun Shu, Dongfang Shi, Jing Yu, Guiqin Fan, Qiuhong Qian, Luhong Shen, Bing Lu
Transcriptomic analysis reveals the potential crosstalk genes and immune relationship between Crohn’s disease and atrial fibrillation
Xiaohan Qiu, Junlin Teng, Ning Wang, Luying Cao, Congyi Cheng, Cong Su, Youran Dong, Fen Wang, Wenqiang Chen
A closed surgical intensive care unit organization improves cardiac surgical patient outcomes
Lauren A. Johnson, Brianna Klucher, Hanna Jensen, Rebecca Reif, Kyle J. Kalkwarf, Kevin Sexton, Mary Katherine Kimbrough
Frequency and predictive factors of nodal micro-metastasis (NMM) in resectable non-small cell lung cancer
Sophon Siwachat, Apichat Tantraworasin, Nirush Lertprasertsuke, Somcharoen Saeteng
Veno-venous extra-corporeal membrane oxygenation in complex tracheobronchial resection
Luca Voltolini, Alberto Salvicchi, Alessandro Gonfiotti, Sara Borgianni, Giovanni Cianchi, Giovanni Mugnaini, Stefano Bongiolatti
Cerebral protection in acute type A aortic dissection surgery: a systematic review and meta-analysis
Mehran Rahimi, Hadi Sahrai, Ali Norouzi, Mohammadreza Taban-Sadeghi, Ahmadali Khalili, Sina Hamzehzadeh, Reza Ali Akbari Khoei, Hossein Hosseinifard, Ralf Martz Sulague, Jacques Kpodonu
More attention should be paid to Omicron-associated sepsis: a multicenter retrospective study in south China
Ling Sang, Yonghao Xu, Yongbo Huang, Zhengtu Li, Deliang Wen, Changbo Liu, Yichun Wang, Lewu Xian, Linling Cheng, Feng Ye, Hongkai Wu, Xilong Deng, Yueping Li, Weiyan Ye, Nanshan Zhong, Yimin Li, Shiyue Li, Xiaoqing Liu
Enhanced recovery after surgery pathway leads to decreased length of stay for patients undergoing minimally invasive lung resection
Madeline L. Fryer, Benjamin A. Palleiko, Isabel Emmerick, Allison Crawford, Mamatha Kadiyala, Feiran Lou, Karl Uy, Mark W. Maxfield
Differential response to roflumilast in patients with chronic obstructive pulmonary disease: real-world evidence
Hyun Woo Lee, Jiyu Sun, Hyo-Jin Lee, Jung-Kyu Lee, Tae Yeon Park, Eun Young Heo, Chin Kook Rhee, Deog Kyeom Kim
Investigating the multitarget pharmacological mechanism of Rhodiola wallichiana var. cholaensis acting on angina pectoris using combined network pharmacology and molecular docking
Haitao Zhang, Xudong Zhuang, Zhixiong Li, Xinrui Wang
Effect of prone positioning on survival in adult patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a prospective multicenter randomized controlled study
Hongjie Tong, Feiyan Pan, Xiaoling Zhang, Shengwei Jia, Rishik Vashisht, Kun Chen, Qianqian Wang
Feasibility and performance of the chronic obstructive pulmonary disease population screener and chronic obstructive pulmonary disease screening questionnaire in a Chinese physical examination center
Xiaoqing Huang, Hanguang Yu, Enmin Huang, Shuqian Wang, Jiali Chen, Jinweng Weng, Peter S. P. Cho, Mi Hyoung Moon, Mei Song, Xueying Fang
Modified surgical incision suturing technique in uniportal video-assisted thoracoscopic pulmonary resection
Liuying Pan, Tengfei Chen, Zhipan Liang, Piergiorgio Solli, Benedetta Bedetti, Kyung Soo Kim, Xiaowei She
Improvement of idiopathic pulmonary fibrosis through a combination of Astragalus radix and Angelica sinensis radix via mammalian target of rapamycin signaling pathway-induced autophagy in rat
Chao Sun, Huaman Liu, Baihong Chi, Jia Han, Yasuhiko Koga, Kamyar Afshar, Xue Liu
Mebendazole induces apoptosis and inhibits migration via the reactive oxygen species-mediated STAT3 signaling downregulation in non-small cell lung cancer
Zhipan Liang, Qiuyun Chen, Liuying Pan, Xiaowei She, Tengfei Chen
Promotion of non-small cell lung cancer tumor growth by FHL2 via inducing angiogenesis and vascular permeability
Tengfei Chen, Jun Chen, Qiuyun Chen, Zhipan Liang, Liuying Pan, Jun Zhao, Xiaowei She
Identification of prognostic biomarkers of smoking-related lung cancer
Chen Liang, Wei Pan, Zhijun Zhou, Xiaomin Liu
Long-term prognosis analysis of surgical therapy for bilateral synchronous multiple primary lung cancer: a follow-up of 293 cases
Hui Zhang, Lian Chen, Feng Mao, Jiantiao Li, Masatsugu Hamaji, Yoshihisa Shimada, Chi Wan Koo, Zuodong Song, Liwei Song, Shun Lu
Bioinformatics analysis of the prognostic role of alternative splicing data in lung adenocarcinoma
Lingling Zhao, Shuting He, Ziwei Liu, Zhibin Song, Xiaochun Hou, Ling Gai
Effects of case volume on short- and long-term outcomes following cadaveric lung transplantation in Japan
Masayuki Chida, Takashi Inoue, Takahiro Nakajima, Yoshinori Okada, Hisashi Oishi, Jun Nakajima, Masaaki Sato, Ichiro Yoshino, Hidemi Suzuki, Daisuke Nakajima, Yasushi Shintani, Takashi Kanou, Shinichi Toyooka, Kentaroh Miyoshi, Takeshi Shiraishi, Toshihiko Sato, Keitaro Matsumoto, Takeshi Nagayasu, Yasushi Hoshikawa, Yasushi Matsuda, Sumiko Maeda, Hiroshi Date

Study Protocol

Myocardial protection: comparing histological effects of single-dose cardioplegic solutions—study protocol for a secondary analysis of the CARDIOPLEGIA trial
Kathize Betti Lira, Renan Senandes Delvaux, Felipe Abatti Spadini, Luis Henrique Hauschild, Rafael Oliveira Ceron, Fernando Anschau, Luciane Kopittke, Juarez Rode, Rafael Antônio Widholzer Rey, Estefania Inez Wittke, Alfeu Roberto Rombaldi, Eduardo Cambruzzi, Eron Rodrigues Cunha Lopes, Adriana Silveira Almeida

Surgical Technique

Modified open-thoracotomy-view approach in robotic-assisted thoracoscopic lung resection
Keisei Tachibana, Jun Miura, Yoshifumi Hirata, Kazuharu Suda, Kohei Hashimoto, Ryota Tanaka, Haruhiko Kondo

Review Article

Postoperative atrial fibrillation (POAF) after cardiac surgery: clinical practice review
Orlando R. Suero, Ahmed K. Ali, Lauren R. Barron, Matthew W. Segar, Marc R. Moon, Subhasis Chatterjee
Tackling complex thoracic surgical operations with robotic solutions: a narrative review
Ayham M. Odeh, Kody Wyant, Richard K. Freeman, Zaid M. Abdelsattar
Incidental pulmonary nodule management in Canada: exploring current state through a narrative literature review and expert interviews
Geneviève C. Digby, Jeffrey Habert, Jyoti Sahota, Lucía Zhu, Daria Manos
Developing technologies and areas of interest in lung cancer screening adjuncts
Ju Ae Park, Duy Pham, Sriya Yalamanchili, Shaina Twardus, Kei Suzuki
Optimal antithrombotic strategy following valve-in-valve transcatheter aortic and mitral valve replacement
Maximilian Reisinger, Polydoros N. Kampaktsis, Tanush Gupta, Isaac George
Impact of the COVID-19 pandemic on esophageal cancer resource allocation: a systematic review
Nicholas M. Fialka, Ryaan El-Andari, Uzair Jogiat, Eric L. R. Bédard, Bryce Laing, Jayan Nagendran
The influence of novel coronavirus pneumonia on chronic disease management of asthma—a narrative review
Xue-Fen Chen, Jing-Min Deng
A narrative review of the controversy on the risk of mycobacterial infections with immune checkpoint inhibitor use: does Goldilocks have the answer?
Akshara Vaddi, Holly J. Hulsebus, Emily L. O’Neill, Vijaya Knight, Edward D. Chan
Donor management and extremely high donor lung utilization rate in Japan
Yasushi Hoshikawa, Yasushi Matsuda, Juntaro Ashikari
The effect of infectious diseases on lung transplantation in Japan
Satoshi Kitaura, Koh Okamoto
Chylothorax: pathophysiology, diagnosis, and management—a comprehensive review
Malvika Bhatnagar, Annette Fisher, Sudarshan Ramsaroop, Alison Carter, Benjamin Pippard
Hepatic hydrothorax
Hannah Wilkins, Ellie Britt, Malvika Bhatnagar, Benjamin Pippard
Cardiac related pleural effusions: a narrative review
Thisarana Wijayaratne, Asfandyar Yousuf, Rakesh Panchal
Pectus excavatum and carinatum: a narrative review of epidemiology, etiopathogenesis, clinical features, and classification
Nicky Janssen, Nadine A. Coorens, Aimée J. P. M. Franssen, Jean H. T. Daemen, Iris L. Michels, Karel W. E. Hulsewé, Yvonne L. J. Vissers, Erik R. de Loos
Hybrid ablation for persistent atrial fibrillation: a narrative review
Shohei Kataoka, Morio Shoda, Koichiro Ejima, Ken Kato, Kyoichiro Yazaki, Shun Hasegawa, Masayuki Sakai, Satoshi Higuchi, Daigo Yagishita, Junichi Yamaguchi
Chest wall resections for sulcus superior tumors
Semih Ünal, David Jonathan Heineman, Martijn van Dorp, Toon Winkelman, Jerry Braun, Max Dahele, Chris Dickhoff
Sternal cleft: new options for reconstruction
João Paulo Cassiano de Macedo, Pedro Henrique Xavier Nabuco de Araujo, José Ribas Milanez de Campos, Paulo Manuel Pêgo-Fernandes

Editorial

Chest wall resections and reconstructions
Jean H. T. Daemen, Jose R. Milanez de Campos, Erik R. de Loos

Original Article

Nonintubated thoracoscopic lung resection: a 3-year experience with 285 cases in a single institution
Ke-Cheng Chen, Ya-Jung Cheng, Ming-Hui Hung, Yu-Ding Tseng, Jin-Shing Chen
Delays in the diagnosis of lung cancer
Peter M Ellis, Rachel Vandermeer
The diagnostic utility of endobronchial ultrasonography with a guide sheath and tomosynthesis images for ground glass opacity pulmonary lesions
Takehiro Izumo, Shinji Sasada, Christine Chavez, Takaaki Tsuchida
Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer
Keiko Muraki, Ryo Koyama, Yuichiro Honma, Shigehiro Yagishita, Takehito Shukuya, Rina Ohashi, Fumiyuki Takahashi, Kenji Kido, Shin-ichiro Iwakami, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi
Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung
Deepinder Singh, Yuhchyau Chen, Mary Z. Hare, Kenneth Y. Usuki, Hong Zhang, Thomas Lundquist, Neil Joyce, Michael C. Schell, Michael T. Milano
Theoretical models of carcinogenic particle deposition and clearance in children’s lungs
Robert Sturm
A novel paradigm in the treatment of oligometastatic non-small cell lung cancer
Salma K Jabbour, Parima Daroui, Dirk Moore, Edward Licitra, Molly Gabel, Joseph Aisner
Radiotherapy for a second primary lung cancer arising post-pneumonectomy: planning considerations and clinical outcomes
Sashendra Senthi, Cornelis J. A. Haasbeek, Frank J. Lagerwaard, Wilko F. Verbakel, Patricia F. de Haan, Ben J. Slotman, Suresh Senan
Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiation
Inaya Ahmed, Adam Ferro, Alan Cohler, John Langenfeld, Sujani G. Surakanti, Joseph Aisner, Wei Zou, Bruce G. Haffty, Salma K. Jabbour
Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis: a multicentre Australian experience
James Geake, Gary Hammerschlag, Phan Nguyen, Peter Wallbridge, Grant A. Jenkin, Tony M. Korman, Barton Jennings, Douglas F. Johnson, Louis B. Irving, Michael Farmer, Daniel P. Steinfort
Comparative outcomes of squamous and non-squamous non-small cell lung cancer (NSCLC) patients in phase II studies of ASA404 (DMXAA) – retrospective analysis of pooled data
Mark J McKeage, Michael B Jameson, AS1404-201 Study Group Investigators
High prevalence of gene abnormalities in young patients with lung cancer
Osamu Nagashima, Rina Ohashi, Yasuko Yoshioka, Ai Inagaki, Manabu Tajima, Yoshika Koinuma, Shin-ichiro Iwakami, Akihiko Iwase, Shinichi Sasaki, Shigeru Tominaga, Kazuhisa Takahashi
Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients
Amy J. Hoffman, Ruth Ann Brintnall, Alexander von Eye, Lee W. Jones, Gordon Alderink, Lawrence H. Patzelt, Jean K. Brown
Thoracic malignant solitary fibrous tumors: A population-based study of survival
Michael T Milano, Deepinder P Singh, Hong Zhang
Differences in chemosensitivity between primary and paired metastatic lung cancer tissues: In vitro analysis based on the collagen gel droplet embedded culture drug test (CD-DST)
Masahiko Higashiyama, Jiro Okami, Jun Maeda, Toshiteru Tokunaga, Ayako Fujiwara, Ken Kodama, Fumio Imamura, Hisayuki Kobayashi
High-resolution CT findings of patients with pulmonary nocardiosis
Naoki Tsujimoto, Takeshi Saraya, Ken Kikuchi, Saori Takata, Yasuyuki Kurihara, Sayuki Hiraoka, Hiroshi Makino, Shota Yonetani, Koji Araki, Haruyuki Ishii, Hajime Takizawa, Hajime Goto
Signal stratification of autoantibody levels in serum samples and its application to the early detection of lung cancer
Graham F. Healey, Stephen Lam, Peter Boyle, Geoffrey Hamilton-Fairley, Laura J. Peek, John F. R. Robertson

Review Article

Molecular biology of lung cancer
Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna
Nontuberculous mycobacterial pulmonary infections
Margaret M. Johnson, John A. Odell
Treatment of advanced non small cell lung cancer
Maria Anna Bareschino, Clorinda Schettino, Antonio Rossi, Paolo Maione, Paola Claudia Sacco, Rosario Zeppa, Cesare Gridelli
Chemotherapy advances in small-cell lung cancer
Bryan A. Chan, Jermaine I. G. Coward
Electromagnetic navigation bronchoscopy: A descriptive analysis
Steven Leong, Hong Ju, Henry Marshall, Rayleen Bowman, Ian Yang, Ann-Maree Ree, Cathy Saxon, Kwun M Fong
Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer
Peter Savas, Brett Hughes, Benjamin Solomon
Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies
Suresh Senan, David A. Palma, Frank J. Lagerwaard
The anticipation and management of air leaks and residual spaces post lung resection
Michael Rolf Mueller, Beatrice A. Marzluf
Exploiting sensitization windows of opportunity in hyper and hypo-fractionated radiation therapy
Anish Prasanna, Mansoor M. Ahmed, Mohammed Mohiuddin, C. Norman Coleman
Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and how to learn mediastinal endosonography
Christian Jenssen, Jouke Tabe Annema, Paul Clementsen, Xin-Wu Cui, Mathias Maximilian Borst, Christoph Frank Dietrich
Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department
Luciano Cardinale, Giovanni Volpicelli, Alessandro Lamorte, Jessica Martino, Andrea veltri
The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era
Zarnie Lwin, Jonathan W. Riess, David Gandara
MicroRNAs in mesothelioma: from tumour suppressors and biomarkers to therapeutic targets
Glen Reid
Pleural controversies: image guided biopsy vs. thoracoscopy for undiagnosed pleural effusions?
Giles Dixon, Duneesha de Fonseka, Nick Maskell
Preservation solutions for cardiac and pulmonary donor grafts: a review of the current literature
Nicholas Latchana, Joshua R. Peck, Bryan Whitson, Sylvester M. Black
Active-specific immunotherapy for non-small cell lung cancer
Hauke Winter, Natasja K. van den Engel, Margareta Rusan, Nina Schupp, Christian H. Poehlein, Hong Ming Hu, Rudolf A. Hatz, Walter J. Urba, Karl Walter Jauch, Bernard A. Fox, Dominik Rüttinger
Advanced imaging in COPD: insights into pulmonary pathophysiology
Stephen Milne, Gregory G. King
Advances in lung adenocarcinoma classification: a summary of the new international multidisciplinary classification system (IASLC/ATS/ERS)
Elizabeth R. Tang, Andrew M. Schreiner, Bradley B. Pua
Diagnosis and early detection of COPD using spirometry
David P. Johns, Julia A.E. Walters, E. Haydn Walters
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Pediatric lung transplantation: indications and outcomes
Stephen Kirkby, Don Hayes Jr
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
JTD special edition ‘Hot Topics in COPD’—The microbiome in COPD
Daniel C. Chambers, Shaan L. Gellatly, Philip Hugenholtz, Philip M. Hansbro
Lung donor selection criteria
John Chaney, Yoshikazu Suzuki, Edward Cantu III, Victor van Berkel
Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer
Joshua D. Palmer, Nicholas G. Zaorsky, Matthew Witek, Bo Lu
Lung cancer screening: identifying the high risk cohort
Michael W. Marcus, Olaide Y. Raji, John K. Field
Pleural controversies: indwelling pleural catheter vs. pleurodesis for malignant pleural effusions
Marc Fortin, Alain Tremblay
New techniques for assessing response after hypofractionated radiotherapy for lung cancer
Sarah A. Mattonen, Kitty Huang, Aaron D. Ward, Suresh Senan, David A. Palma
Supportive and palliative care for lung cancer patients
Patsy Yates, Penelope Schofield, Isabella Zhao, David Currow

Case Report

First report of a novel liquid nitrogen adjustable flow spray cryotherapy (SCT) device in the bronchoscopic treatment of disease of the central tracheo-bronchial airways
Robert Browning, Scott Parrish, Saiyad Sarkar, J. Francis Turner Jr
Severe amiodarone induced pulmonary toxicity
Nicholas Nacca, Castigliano M Bhamidipati, Luke S Yuhico, Sowmya Pinnamaneni, Tamas Szombathy

Guideline

Guidelines for the diagnosis and treatment of malignant pleural mesothelioma
Nico van Zandwijk, Christopher Clarke, Douglas Henderson, A. William Musk, Kwun Fong, Anna Nowak, Robert Loeragan, Brian McCaughan, Michael Boyer, Malcolm Feigen, David Currow, Penelope Schofeild, Beth Ivimey Nick Pavlakis, Jocelyn McLean, Henry Marshall, Steven Leong, Victoria Keena, Andrew Penman

Research Highlight

Gene expression assays as prognostic and predictive markers in early stage non-small cell lung cancer
Tom Donnem, Roy M Bremnes, Lill-Tove Busund, Sigve Andersen, Francesco Pezzella

Short Communication

The sleep apnea cardiovascular endpoints (SAVE) trial: Rationale and start-up phase
R Doug McEvoy, Craig S Anderson, Nick A Antic, Baoyuan Chen, Quanying He, Emma Heeley, Shaoguang Huang, Yining Huang, Jiguang Wang, Nanshan Zhong

Circulating Tumor Cells

Detection methods of circulating tumor cells
Klaus Pantel, Catherine Alix-Panabières

Original Article

Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury
Julia Scheiermann, Dennis M. Klinman
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success
Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander Sasha Krupnick
A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy
Matthew A. Gubens, Jody C. Chuang, Wallace Akerley, Corey J. Langer, Christelle Clément- Duchêne, Melanie San Pedro-Salcedo, A. Dimitrios Colevas, Konstantin Dragnev, Mark A. Socinski, Heather A. Wakelee
Pleurodesis: a comparison of two sclerosing agents for pleural effusions in Mozambique
Ivo Figueiredo, Anilsa Cossa, Anila Hassane, José Sousa, Joaquim Pondo, João Teixeira, Kevan Akrami, Susannah K. Graves, Atul Malhotra, Elizabete A. Nunes

Review Article

Atypical antibody responses to influenza
Dalton Hermans, Richard J. Webby, Sook-San Wong
What can individuals do to reduce personal health risks from air pollution?
Robert Laumbach, Qingyu Meng, Howard Kipen
The role of rotors in atrial fibrillation
David E. Krummen, Vijay Swarup, Sanjiv M. Narayan
Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials
Daniel Fudulu, Umberto Benedetto, Gustavo Guida Pecchinenda, Pierpaolo Chivasso, Vito Domenico Bruno, Filippo Rapetto, Alan Bryan, Gianni Davide Angelini
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Esophageal cancer: staging system and guidelines for staging and treatment
Mark F. Berry
Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts
Ming-Ching Lee, Kyuichi Kadota, Daniel Buitrago, David R. Jones, Prasad S. Adusumilli
Premature menopause in young breast cancer: effects on quality of life and treatment interventions
Shoshana M. Rosenberg, Ann H. Partridge
Strategies for the acquisition of transcriptional and epigenetic information in single cells
Guang Li, Elda Dzilic, Nick Flores, Alice Shieh, Sean M. Wu
The role of transforming growth factor (TGF)-β in the infarcted myocardium
Nikolaos G. Frangogiannis
Utility of cardiac magnetic resonance for evaluation of mitral regurgitation prior to mitral valve surgery
Neil K. Mehta, Jiwon Kim, Jonathan Y. Siden, Sara Rodriguez-Diego, Javid Alakbarli, Antonino Di Franco, Jonathan W. Weinsaft
Adjuvant, neoadjuvant, and definitive radiation therapy for malignant pleural mesothelioma
Gwendolyn Cramer, Charles B. Simone II, Theresa M. Busch, Keith A. Cengel

Editorial

Conservatism strikes back: later is better than earlier dialysis for acute kidney injury
Dana Bielopolski, Kamyar Kalantar-Zadeh
Sleep and critical illness: bridging the two pillars at the ATS 2016
Stuti J. Jaiswal, Atul Malhotra, Robert L. Owens
Temperature and duration targets during post-arrest care: choosing the right prescription for the right patient
John C. Greenwood, Abhishek Bhardwaj, Benjamin S. Abella
Examining the paradox of high high-density lipoprotein and elevated cardiovascular risk
Kavisha Singh, Anand Rohatgi
Mortality after red blood cell transfusions from previously pregnant donors: complexities in the interpretation of large data
Susan Kuldanek, Christopher C. Silliman
Optogenetic tools for cell biological applications
Abhirup Mukherjee, Nicole A. Repina, David V. Schaffer, Ravi S. Kane
Editorial on “Transcription factor SPZ1 promotes TWIST-mediated epithelial—mesenchymal transition and oncogenesis in human liver cancer”
Dan J. Raz
Editorial on “Can CT-PET and endoscopic assessment post-neoadjuvant chemoradiotherapy predict residual disease in esophageal cancer”
Chia-Ju Liu, Wei Lu
The hemodynamic impact of acute nasal continuous positive airway pressure treatment in hypertrophic cardiomyopathy: is it safe?
Bo Xu, Reena Mehra
Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma
Hui-Zi Chen, Erin M. Bertino, Kai He
Antiviral prophylaxis of cytomegalovirus reactivation in immune competent patients—the jury remains out
Sara A. Mansfield, Charles H. Cook
Allosterically targeting EGFR drug-resistance gatekeeper mutations
Nicholas Spellmon, Chunying Li, Zhe Yang
Imaging homeostatic sleep pressure and circadian rhythm in the human brain
Zhuo Fang, Hengyi Rao
Tumor mutational burden (TMB) as a biomarker of response to immunotherapy in small cell lung cancer
Yanis Boumber

Letter to the Editor

Response to “VATS vs. thoracotomy regarding postoperative chronic pain”
Emine Ozgur Bayman, Kalpaj R. Parekh, John Keech, Timothy J. Brennan
The role of a decision analysis in treatment of T2N0 esophageal cancer
Tara R. Semenkovich, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri

Case Report

Intraoperative near-infrared imaging can identify subcentimeter colorectal cancer lung metastases during pulmonary metastasectomy
Andrew D. Newton, Jarrod D. Predina, Lydia G. Frenzel-Sulyok, Michael H. Shin, Yiqing Wang, Sunil Singhal
A novel strategy for cardiopulmonary support during lung transplantation
Ramiro Fernandez, Malcolm M. DeCamp, Ankit Bharat

Review Article on Left Ventricular Assist Devices

Left ventricular assist device driveline infections: recent advances and future goals
Anne-Marie Leuck

Short Communication of Interventional Pulmonology Corner

Endobronchial ultrasound—guidance for interstitial photodynamic therapy of locally advanced lung cancer—a new interventional concept
Kassem Harris, Emily Oakley, David Bellnier, Gal Shafirstein

Below are the latest Journal of Thoracic Disease articles published online ahead of print publication.